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Vince Young vs. Alex Smith.

That's the matchup Sunday at the 'Stick when the Titans visit to play the 49ers. Young and Smith are former high draft picks who lost their starting jobs for various reasons.

Now, both are trying to remake their careers with their original teams. Both made their first starts of the season a week ago.

Young, the No. 3 overall pick in the 2006 draft, lost his starting job to Kerry Collins. With mostly Collins at the controls, the Titans went 13-3 but lost in the first round of the playoffs.

But when Young was playing, the Titans have always been effective. In fact, Young's regular-season record as a starter is now 19-11 with last week's 30-13 victory over the Jaguars. (It didn't hurt matters that running back Chris Johnson gained 228 yards on 24 rushes).

This is Jeff Fisher's 16^th season as a head coach in the NFL. During that time the former 49ers assistant has faced San Francisco just three times.

"As I told our team this morning, this is a team that we know nothing about," Fisher said this morning a handful of Bay Area newspaper reporters during the weekly conference call with the opposing coach.